EFFECT OF OMEGA-3 FATTY ACID SUPPLEMENTATION AND A CONTROLLED-RELEASE INTRAMUSCULAR THYROXINE INJECTION ON SERUM INSULIN CONCENTRATIONS IN HORSES

dc.contributor.advisorBaker, Lance
dc.creatorChewning, Shayna N.
dc.creator.orcid0000-0001-8804-9041
dc.date.accessioned2018-12-19T15:09:21Z
dc.date.available2018-12-19T15:09:21Z
dc.date.created2018-08
dc.date.issued2018-12-13
dc.date.submittedAugust 2018
dc.date.updated2018-12-19T15:11:31Z
dc.description.abstractA completely randomized design experiment was conducted to examine the effects of omega-3 fatty acid and thyroxine supplementation on serum thyroxine and insulin concentrations in horses. Thirty-thee geldings and 11 mares (aged 5 to 27 yr) were stratified by preliminary 4-h postprandial serum insulin concentration. All horses were then randomly assigned to 1 of 3 treatments: control (C), daily oral omega-3 PUFA supplementation (O), or monthly controlled release IM thyroxine microparticle injection (T). The 114-d trial consisted of a d 0 baseline sample, followed by a 30-d and 3 subsequent 28-d periods, named for the month in which the sample was collected – August, September, October, November and December. At the beginning of each period, venous blood was collected to determine serum thyroxine and insulin concentrations. Thyroxine-treated horses had greater (P < 0.001) serum thyroxine concentrations compared to both C and O horses. Thyroxine-treated horses also had decreased (P = 0.001) serum insulin concentrations compared to both C and O horses. Results from this experiment indicate that IM thyroxine microparticle injection is an effective method of increasing serum thyroxine concentrations results in decreased serum insulin concentrations compared to untreated animals.
dc.format.mimetypeapplication/pdf
dc.identifier.urihttps://hdl.handle.net/11310/171
dc.language.isoen_US
dc.subjecthorse
dc.subjectinsulin
dc.subjectomega-3 fatty acid
dc.subjectoral glucose challenge
dc.subjectthyroxine
dc.titleEFFECT OF OMEGA-3 FATTY ACID SUPPLEMENTATION AND A CONTROLLED-RELEASE INTRAMUSCULAR THYROXINE INJECTION ON SERUM INSULIN CONCENTRATIONS IN HORSES
dc.typeThesis
dc.type.materialtext
thesis.degree.departmentAgricultural Sciences
thesis.degree.disciplineAnimal Science
thesis.degree.grantorWest Texas A&M University
thesis.degree.levelMasters
thesis.degree.nameM. S.

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